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Hiroshi Hisajima Selected Research

8- (4- fluorophenyl)- 2- (3- phenyl- 2- propenoyl)- 1,2,3,4- tetrahydropyrazolo(5,1- c)(1,2,4)triazine

12/2003A novel potent radical scavenger, 8-(4-fluorophenyl)-2-((2E)-3-phenyl-2-propenoyl)-1,2,3,4-tetrahydropyrazolo[5,1-c] [1,2,4]triazine (FR210575), prevents neuronal cell death in cultured primary neurons and attenuates brain injury after focal ischemia in rats.

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Hiroshi Hisajima Research Topics

Disease

1Brain Injuries (Brain Injury)
12/2003
1Brain Ischemia (Cerebral Ischemia)
12/2003
1Ischemia
12/2003
1Reperfusion Injury
12/2003
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2003
1Stroke (Strokes)
12/2003

Drug/Important Bio-Agent (IBA)

18- (4- fluorophenyl)- 2- (3- phenyl- 2- propenoyl)- 1,2,3,4- tetrahydropyrazolo(5,1- c)(1,2,4)triazineIBA
12/2003
1TriazinesIBA
12/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2003
1Neuroprotective AgentsIBA
12/2003

Therapy/Procedure

1Intravenous Infusions
12/2003